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ATRANORIN

Product Name
ATRANORIN
CAS No.
479-20-9
Chemical Name
ATRANORIN
Synonyms
Atrarin;USNARIN;PARMELIN;ATRANORIN;NSC-685591;ATRANORIN(P);3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat;3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 3-formyl-2,4-dihydroxy-6-methylbenzoate;Benzoic acid,3-formyl-2,4-dihydroxy-6-methyl-,3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester;3-Formyl-2,4-dihydroxy-6-methylbenzoic acid 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester
CBNumber
CB6665973
Molecular Formula
C19H18O8
Formula Weight
374.34
MOL File
479-20-9.mol
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ATRANORIN Property

Melting point:
156-158°C
storage temp. 
Store at -20°C
solubility 
Chloroform: soluble,DMSO: soluble
form 
A crystalline solid
LogP
6.140 (est)
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Safety

Toxicity
skn-gpg 5% CODEDG 11,168,1984
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL84203
Product name
Atranorin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$574
Updated
2024/03/01
Cayman Chemical
Product number
28106
Product name
Atranorin
Packaging
500μg
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
28106
Product name
Atranorin
Packaging
1mg
Price
$90
Updated
2024/03/01
Cayman Chemical
Product number
28106
Product name
Atranorin
Packaging
5mg
Price
$236
Updated
2024/03/01
Cayman Chemical
Product number
28106
Product name
Atranorin
Packaging
10mg
Price
$331
Updated
2024/03/01
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ATRANORIN Chemical Properties,Usage,Production

Description

Atranorin is a depside lichen metabolite that has been found in S. alpinum and has diverse biological activities. It is active against the bacteria B. cereus, B. subtilis, S. aureus, S. faecalis, P. vulgaris, L. monocytogenes, and A. hydrophila (MICs = 1.67, 0.38, 26.7, 13.4, 3.34, 9.83, and 1.67 mM, respectively), the fungi C. albicans and C. glabrata (MIC = 26.7 mM for both), as well as the mycobacterium M. aurum (MIC = 250 μg/ml). Atranorin is cytotoxic to A270, HL-60, and Jurkat cancer cells (IC50s = 197.9, 93.5, and 181.6 μM, respectively) but not HeLa, MCF-7, SK-BR-3, or HT-29 cancer cells (IC50s = >200 μM). It inhibits acetic acid-induced writhing in mice when administered orally at doses of 200 and 400 mg/kg. Atranorin (200 and 400 mg/kg, p.o.) also reduces paw licking and biting in the second, but not first, phase of the formalin test when administered 30 minutes prior to formalin in mice.

Uses

antinociceptive, antiinflammatory, antibacterial

Uses

Component in extracts of oak moss used as fragrance. Atranorin is a derivative compound of Chloratranorin (C364120), which are metabolites of Evernia prunastri and functions as antioxidant, antimicrobial and potential anticancer agents.

Definition

ChEBI: Atranorin is a carbonyl compound.

Hazard

A poison by skin contact. A skin irritant.

Safety Profile

A poison by skin contact. A skin irritant. When heated to decomposition it emits acrid smoke and irritating vapors.

ATRANORIN Preparation Products And Raw materials

Raw materials

Preparation Products

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ATRANORIN Suppliers

China 65 China Hong Kong 1 Germany 1 Switzerland 1 United Kingdom 4 United States 13 USA 1 Global 86
TopScience Biochemical
Tel
00852-68527855
Fax
00852-26406298
Email
info@itopbiochem.com
Country
China Hong Kong
ProdList
902
Advantage
58
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View Lastest Price from ATRANORIN manufacturers

Career Henan Chemical Co
Product
ATRANORIN 479-20-9
Price
US $8.00/KG
Min. Order
1KG
Purity
＞98% HPLC
Supply Ability
20 tons
Release date
2020-02-17

479-20-9, ATRANORINRelated Search:

Methyl 3-methylbenzoate 2,5-Dimethylbenzaldehyde 3-Hydroxyphenyl acetate 4-Methoxy-3-methylbenzoic acid RESORCINOL MONOBENZOATE 3-Benzyloxyphenol P-TOLYL BENZOATE METHYL 2,4-DIHYDROXY-3,6-DIMETHYLBENZOATE METHYL 4-BENZYLOXYBENZOATE 2,5-Dimethylphenol 2,3,6-Trimethylphenol 2,4-DIHYDROXY-3,6-DIMETHYLBENZOIC ACID 4-METHOXY-2-METHYLBENZALDEHYDE 4-HYDROXY-3-METHYL-BENZOIC ACID METHYL ESTER 4-BENZYLOXY-2-HYDROXYBENZALDEHYDE Methyl salicylate ATRANORIN 4-BENZYLOXYBENZYL ALCOHOL

  • PARMELIN
  • USNARIN
  • ATRANORIN
  • 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl 3-formyl-2,4-dihydroxy-6-methylbenzoate
  • 3-Formyl-2,4-dihydroxy-6-methylbenzoic acid 3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester
  • NSC-685591
  • ATRANORIN(P)
  • Atrarin
  • Benzoic acid,3-formyl-2,4-dihydroxy-6-methyl-,3-hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl ester
  • 4-[(3S,5R,8R,9S,10S,12R,13S,14S,17R)-3,12,14-trihydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2-oxolanone
  • 3-Hydroxy-4-(methoxycarbonyl)-2,5-dimethylphenyl-3-formyl-2,4-dihydroxy-6-methylbenzoat
  • 479-20-9